NEFL antibody (AA 400-543)

Catalog No. ABIN5699797

This Rabbit Polyclonal antibody specifically detects NEFL in WB, IHC, IF, ELISA and IP. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for NEFL antibody (AA 400-543) (ABIN5699797)

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEFL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

Product Details anti-NEFL Antibody

Binding Specificity: AA 400-543

Purpose: NEFL antibody

Immunogen:

Immunogen sequence: 400-543aa

Immunogen: neurofilament, light polypeptide

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:100 - 1:500, IF: 1:50 - 1:200

Comment:

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab05710(NEFL antibody) at dilution of 1:4000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for NEFL

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Alternative Name: NEFL

Background:

Synonyms: Neurofilament light polypeptide (NF-L)|68 kDa neurofilament protein|Neurofilament triplet L protein|NEFL|NF68|NFL

Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Molecular Weight: 65-68 kDa,140-160 kDa

UniProt: P07196